An Australian biotechnology firm said on Thursday that it had developed a means of delivering anti-cancer drugs directly to cancer cells, aiming to avoid the debilitating toxicity associated with chemotherapy.
The method use nanotechnology which involves micro machines far smaller than a human cell Direct targeting of chemotherapy drugs would allow dosages thousands of times lower than that in conventional chemotherapy and be more easily tolerated by patients said the firm.
Writing in the June issue o US based Cancer Cell magazine the biotech firm EnGenel IC said it had developed neon-cell containing chemotherapy drugs
Via antibodies on their surface these nano-cell target and latch on to cancer cells. Once attached on to cancer cells is engulfed and the drug in released idirecty inside the cancer cell.
The firm said the the bacterially derived nano-cell called EnGane-IC delivery vehicles had proven safe in primate trials had proven safe in primate trials and result in significant cancer regression. It hoped to carry out human trails later in 2007. If it gained approval from Australian. US European and Japanese regulatory authorize.
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